À propos de l'instructeur :
Sonia Enosse, Ph.D. in Molecular Epidemiology from the University of Copenhagen, joined in 1999 the Mozambique National Institute of Health (INS) as a researcher, making significant contributions to the field of Malaria epidemiology and drug resistance. From 2001-2006 worked as a research associate at the Mozambique Manhiça Health Research Center(CISM). Member of the country Malaria Scientific Committee and the Mozambique Academy of Science. In 2022, joined Malaria Consortium (MC) as the Country Technical Coordinator, overseeing projects implemented by MC in Mozambique in the field of Malaria and associated health inequities. Investigator in research studies to evaluate the effectiveness and viability of implementing Seasonal Malaria Chemoprevention in Mozambique and coordinate the implementation of the strategy at MC; and interested in surveillance to ensure data quality and data use to inform strategies.
Timóteo A. Sambo is a MaModAfrica PhD candidate in Malaria Modelling, registered at the Nelson Mandela African Institution of Science and Technology, Tanzania. His research focuses on the use of routine surveillance data and mathematical modelling to evaluate and optimize SMC deployment in Mozambique.
Résumé du séminaire
An overview of Seasonal Malaria Chemoprevention (SMC) from implementation studies to scale-up.
The presentation by Sonia Maria Enosse of Malaria Consortium details the implementation and impact of Seasonal Malaria Chemoprophylaxis (SMC) in Mozambique, with a focus on Nampula Province. Through clinical trials and pilot studies conducted between 2020 and 2024, it was demonstrated that the monthly administration of SPAQ to children under five reduced the incidence of clinical malaria by up to 86%, proving to be a highly cost-effective strategy that is well accepted by local communities. Despite challenges related to drug resistance to sulfadoxine-pyrimethamine and the operational complexities of digitizing campaigns, the results support the consolidation of QSM as a vital intervention in the National Strategic Plan for Malaria Control, with recommendations for its geographic expansion to provinces such as Niassa and Cabo Delgado, as well as the enhancement of supervision and monitoring based on real-time data.
Assessing the effectiveness of Seasonal Malaria Chemoprevention in northern Mozambique with routine surveillance data.
The presentation analyzes the impact of Seasonal Malaria Chemoprophylaxis (SMC) in Nampula, Mozambique, using routine data and a Controlled Interrupted Time Series (CITS) approach. Although Round 1 did not show a measurable effect, Round 2 demonstrated a statistically significant impact, attributed to operational improvements, greater coverage, and scale. The study highlights the importance of triangulating routine data with climatic factors and other interventions, the need for continued investment in the digitization of health data, and the need for caution in interpreting results due to challenges such as data quality and sample size.
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