Retrospective and prospective impact of SMC in Mozambique

When

May 5, 2026

Time

15hr UTC

Zoom

Categories

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About the instructor:

Sonia Enosse, Ph.D. in Molecular Epidemiology from the University of Copenhagen, joined in 1999 the Mozambique National Institute of Health (INS) as a researcher, making significant contributions to the field of Malaria epidemiology and drug resistance. From 2001-2006 worked as a research associate at the Mozambique Manhiça Health Research Center(CISM). Member of the country Malaria Scientific Committee and the Mozambique Academy of Science. In 2022, joined Malaria Consortium (MC) as the Country Technical Coordinator, overseeing projects implemented by MC in Mozambique in the field of Malaria and associated health inequities. Investigator in research studies to evaluate the effectiveness and viability of implementing Seasonal Malaria Chemoprevention in Mozambique and coordinate the implementation of the strategy at MC; and interested in surveillance to ensure data quality and data use to inform strategies.

Timóteo A. Sambo is a MaModAfrica PhD candidate in Malaria Modelling, registered at the Nelson Mandela African Institution of Science and Technology, Tanzania. His research focuses on the use of routine surveillance data and mathematical modelling to evaluate and optimize SMC deployment in Mozambique.

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Presentation Slides

Event Summary

An overview of Seasonal Malaria Chemoprevention (SMC) from implementation studies to scale-up.

Malaria in Mozambique continues to be highly endemic especially in the north and along the coast where the prevalence is highest.  Malaria transmission is perennial in much of the country, with seasonal peaks in the north and north-west between December and April/May. Seasonal malaria chemoprevention (SMC) was first introduced in Mozambique in 2020/21 as part of an implementation study in Nampula province. Following the demonstration of its feasibility, acceptability and effectiveness,  in 2022/23 the intervention was scaled to all 23 districts of Nampula province in Northern Mozambique and after in 2024/25 was extended to other provinces following its inclusion in the  Mozambique National Malaria strategic plan as one of the malaria prevention strategy. In 2024, SMC transitioned from paper-based to digital data collection using the DIGIT Health Campaign Management platform. This presentation shares lessons learned from the scale-up of seasonal malaria chemoprevention implemented in Nampula province, Mozambique.

Assessing the effectiveness of Seasonal Malaria Chemoprevention in northern Mozambique with routine surveillance data.

In this talk, we present a retrospective impact evaluation of SMC in northern Mozambique using routinely collected health facility data. A controlled interrupted time series approach was applied to assess changes in malaria incidence following phased SMC implementation, accounting for underlying trends, seasonality, and key confounding factors, including climate variability and concurrent interventions. Results suggest a measurable reduction in malaria cases following SMC implementation, with notable heterogeneity across districts and implementation rounds. These findings highlight both the value and the limitations of routine data for impact evaluation and support their use in informing malaria control strategies.

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